I'm at 92% completion with inFamous: Second Son. I'm missing a couple of random combat trophies, but I've never bothered to get them, because the big one I'm missing that I know I won't get is the Silver trophy for finishing the game on Expert Difficulty.
These 3 still bug me to this very day:
Resistance 2 will always be sitting at 90% for me. I had a hard enough time killing people online, so reaching 10,000 kills was just too many for me. It's the only trophy I needed for Platinum and since the servers are shut down, it is now unattainable.
For me, it is Sims 3 on PS3. I own 48 of 51 trophies and just never got around to grinding the other two. Missing out on growing a prefect plant and completing 1000 wishes. I would go back to complete, but would need to buy a PS3 and the game.
Mine is Submerged (a really underrated game, by the way). I’m only missing two trophies, but just never got around to exploring enough to find all the secrets and boat boosts in the game.
I'm one of those people who struggles to replay games they've already beaten just to fulfil a trophy condition, especially if it requires doing a speedrun or something. As a result, I am only a couple trophies short of Platinum in Dishonored: Death of the Outsider and Uncharted: The Lost Legacy.
With so many trophies in my collection, there are a number of "almost Platinums" that haunt me. For Broken Age, I just need to speedrun it in under an hour. For Rogue Legacy, I just need to beat it in less than five lives. The two that bother me the most, however, are Vanquish and Grand Theft Auto IV. In Vanquish, I just need to complete the tactical challenges, and in Grand Theft Auto IV, I was turned off by the exceptionally long grind to max rank in multiplayer. I did everything else, but those last trophies tripped me up on my journey to Platinum.
Oh, I have one that happened recently that made me super sad.